Biodegradable nanoparticles formulated from poly (D,L-lactide-co-glycolide) (PLGA) have been extensively investigated for sustained and targeted/localized delivery of different agents including plasmid DNA, proteins and peptides and low molecular weight compounds. Research about the mechanism of intracellular uptake of nanoparticles, their trafficking and sorting into different intracellular compartments, and the mechanism of enhanced therapeutic efficacy of nanoparticle-encapsulated agent at cellular level is more recent and is the primary focus of the review. Recent studies in our laboratory demonstrated rapid escape of PLGA nanoparticles from the endo-lysosomal compartment into cytosol following their uptake. Based on the above mechanism, various potential applications of nanoparticles for delivery of therapeutic agents to the cells and tissue are discussed.
CBP501 Affinity Peptide |
H-8214.0005 |
Bachem |
5.0mg |
EUR 1198 |
Description: Sum Formula: C68H119N21O25S; CAS# [1351804-17-5] net |
Modified Affinity Purified Avidin |
7-04468 |
CHI Scientific |
2mg |
Ask for price |
Modified Affinity Purified Avidin |
7-04469 |
CHI Scientific |
10mg |
Ask for price |
Modified Affinity Purified Avidin |
7-04470 |
CHI Scientific |
100mg |
Ask for price |
Biotinyl-CBP501 Affinity Peptide |
H-8216.0500 |
Bachem |
0.5mg |
EUR 260 |
Description: Sum Formula: C78H133N23O27S2; CAS# [2022956-39-2] net |
Biotinyl-CBP501 Affinity Peptide |
H-8216.1000 |
Bachem |
1.0mg |
EUR 426 |
Description: Sum Formula: C78H133N23O27S2; CAS# [2022956-39-2] net |
Anti-Flag Affinity Gel |
B23101 |
Bimake |
1 ml Kit |
EUR 483 |
Description: Anti-Flag Affinity Gel is a Protein A purIFied murine IgG2b Monoclonal antibody covalently attached to sepharose 4B wHICh could used on Flag fusion protein purIFication, IP and CO-IP. |
Anti-Flag Affinity Gel |
B23102 |
Bimake |
5 ml Kit |
EUR 1452 |
Description: Anti-Flag Affinity Gel is a Protein A purIFied murine IgG2b Monoclonal antibody covalently attached to sepharose 4B wHICh could used on Flag fusion protein purIFication, IP and CO-IP. |
Affinity column (Empty column for use with affinity supports, 1-2 ml complete with frit, top and bottom closures), 10 columns/pk |
800-300-C1 |
Alpha Diagnostics |
1 pk |
EUR 92 |
Affinity column (Empty column for use with affinity supports, 5-15 ml complete with frit, top and bottom closures), 10 columns/pk |
800-300-C2 |
Alpha Diagnostics |
1 pk |
EUR 103 |
Affinity column (Empty column for use with affinity supports, 0.5-1 ml complete with frit, top and bottom closures), 10 columns/pk |
800-300-C3 |
Alpha Diagnostics |
1 pk |
EUR 92 |
High Affinity cAMP-Specific And IBMX-Insensitive 3',5'-Cyclic Phosphodiesterase 8B (PDE8B) Antibody |
abx031349-400ul |
Abbexa |
400 ul |
EUR 523 |
|
High Affinity cAMP-Specific And IBMX-Insensitive 3',5'-Cyclic Phosphodiesterase 8B (PDE8B) Antibody |
abx031349-80l |
Abbexa |
80 µl |
EUR 286 |
|
Recombinant human High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B |
P2521 |
FN Test |
100ug |
Ask for price |
|
Description: Recombinant protein for human High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B |
Anti-MDCK HCP affinity purified |
MDCK-Gt-AF |
Cygnus Technologies |
1 mg |
EUR 1913 |
|
Description: Anti-MDCK HCP affinity purified by Cygnus Technologies is available in Europe via Gentaur. |
anti-NS/0 Affinity Purified |
N9192-Rb-AF |
Cygnus Technologies |
1 mg |
EUR 1913 |
|
Description: anti-NS/0 Affinity Purified by Cygnus Technologies is available in Europe via Gentaur. |
Anti-HEK293 HCP, affinity purified |
HK293R-AF |
Cygnus Technologies |
1 mg |
EUR 1913 |
|
Description: Anti-HEK293 HCP, affinity purified by Cygnus Technologies is available in Europe via Gentaur. |
Anti-HeLa HCP, Affinity Purified |
HL59/73-AF |
Cygnus Technologies |
1 mg |
EUR 1913 |
|
Description: Anti-HeLa HCP, Affinity Purified by Cygnus Technologies is available in Europe via Gentaur. |
anti-LBR antibody, affinity-purified |
70-301 |
Sceti |
50ug |
EUR 362 |
Description: The anti-LBR antibody, affinity-purified is available in Europe and for worldwide shipping via Gentaur. |
Modified Affinity Purified Avidin Protein |
20-abx263157 |
Abbexa |
-
EUR 1372.00
-
EUR 328.00
-
EUR 230.00
|
|
|
Biotin Modified Affinity Purified Avidin protein |
PROTP02701 |
BosterBio |
Regular: 10mg |
EUR 317 |
Description: Avidin is a basic charged glycoprotein present in the egg white and in some extent in tissues of various animals. Avidin is a homotetrameric protein that contains 4 identical subunits which bind to Biotin with high extent of affinity and specificity consisting of 128 amino acids and has a molecular mass of about 67K Daltons. ;Avidin-Biotin is a modified form of affinity purified avidin that combines the high affinity specific activity of the native egg white avidin to biotin molecule together with a very low background of the streptavidin produced by the bacteria Streptomyces avidinii. |
Anti-Per.C6Ð’ Affinity Purified HRP, Goat |
PC118AF-HRP |
Cygnus Technologies |
1 mg |
EUR 4069 |
|
Description: Anti-Per.C6Ð’ Affinity Purified HRP, Goat by Cygnus Technologies is available in Europe via Gentaur. |
anti-Vero Cell HCP, Affinity Purified |
VC807-AFB |
Cygnus Technologies |
1 mg |
EUR 3453 |
|
Description: anti-Vero Cell HCP, Affinity Purified by Cygnus Technologies is available in Europe via Gentaur. |
Anti-Vero Cell HCP affinity purified |
VC807.5-AF |
Cygnus Technologies |
0.5 mg |
EUR 1605 |
|
Description: Anti-Vero Cell HCP affinity purified by Cygnus Technologies is available in Europe via Gentaur. |
Anti-E. coli HCP, Affinity Purified:HRP |
AP117-HRP |
Cygnus Technologies |
1 mg |
EUR 4069 |
|
Description: Anti-E. coli HCP, Affinity Purified:HRP by Cygnus Technologies is available in Europe via Gentaur. |
High Affinity Choline Transporter (ChT) Antibody |
20-abx176837 |
Abbexa |
|
|
|
High Affinity Choline Transporter (ChT) Antibody |
20-abx172805 |
Abbexa |
|
|
|
Recombinant Protein A-Agarose, affinity matrix |
PRTA15-AS-1 |
Alpha Diagnostics |
1 ml |
EUR 202 |
Recombinant Protein A-Agarose, affinity matrix |
PRTA15-AS-100 |
Alpha Diagnostics |
100 ml |
EUR 6749 |
Recombinant Protein A-Agarose, affinity matrix |
PRTA15-AS-25 |
Alpha Diagnostics |
25 ml |
EUR 1816 |
Recombinant Protein A-Agarose, affinity matrix |
PRTA15-AS-5 |
Alpha Diagnostics |
5 ml |
EUR 529 |
anti-Dnmt1 (1-248) antibody, affinity-purified |
70-201 |
Sceti |
50ug |
EUR 348 |
Description: The anti-Dnmt1 (1-248) antibody, affinity-purified is available in Europe and for worldwide shipping via Gentaur. |
anti-HP1? /CBX5 antibody (rabbit) affinity purified |
70-221 |
Sceti |
50ug |
EUR 296 |
Description: The anti-HP1? /CBX5 antibody (rabbit) affinity purified is available in Europe and for worldwide shipping via Gentaur. |
anti-HP1? /CBX1 antibody (rabbit) affinity purified |
70-223 |
Sceti |
50ug |
EUR 296 |
Description: The anti-HP1? /CBX1 antibody (rabbit) affinity purified is available in Europe and for worldwide shipping via Gentaur. |
anti-HP1? /CBX3 antibody (rabbit) affinity purified |
70-225 |
Sceti |
50ug |
Ask for price |
Description: The anti-HP1? /CBX3 antibody (rabbit) affinity purified is available in Europe and for worldwide shipping via Gentaur. |
Goat Anti-Rabbit IgG, Affinity Purified (Bulk) |
20318-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Sheep Anti-Rabbit IgG, Affinity Purified (Bulk) |
20319-SAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Donkey Anti-Rabbit IgG, Affinity Purified (Bulk) |
20320-DAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Human IgA, Affinity Purified (Bulk) |
10019-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Human IgG, Affinity Purified (Bulk) |
10119-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Rabbit Anti-Human IgG, Affinity Purified (Bulk) |
10119-RAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Donkey Anti-Sheep IgG, Affinity Purified (Bulk) |
30326-CAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Monoclonal Anti-Dog IgE, affinity purified, unlabeled |
30389 |
Alpha Diagnostics |
100 ug |
EUR 347 |
Donkey Anti-Sheep IgG, Affinity Purified (Bulk) |
30518-DAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Rat IgG, Affinity Purified (Bulk) |
50319-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Donkey Anti-Goat IgG, Affinity Purified (Bulk) |
60319-DAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Rabbit Anti-Goat IgG, Affinity Purified (Bulk) |
60319-RAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
High affinity IgE receptor subunit gamma Antibody |
20-abx109873 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx339961 |
Abbexa |
|
|
|
Rat High Affinity Choline Transporter (ChT) Protein |
20-abx653740 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Glutathione-S-transferase (GST) Affinity Purified Antibody |
20-abx137511 |
Abbexa |
-
EUR 829.00
-
EUR 328.00
-
EUR 217.00
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx210412 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx177789 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx177790 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx177791 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx173805 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
abx217256-100ug |
Abbexa |
100 ug |
EUR 439 |
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx326230 |
Abbexa |
|
|
|
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody |
20-abx333790 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Goat Anti-Mouse IgG2b, Affinity Purified (Bulk) |
40123-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Mouse IgG1, Affinity Purified (Bulk) |
40126-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Mouse IgG2a, Affinity Purified (Bulk) |
40127-GAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Sheep Anti-Mouse IgG, Affinity Purified (Bulk) |
43319-SAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Rabbit Anti-Mouse IgG, Affinity Purified (Bulk) |
44319-RAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Goat Anti-Mouse IgG, Affinity Purified (Bulk) |
41319-CAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Donkey Anti-Mouse IgG, Affinity Purified (Bulk) |
42319-DAF-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
Rabbit anti-Mouse Moesin IgG, affinity purified |
MSN11-A |
Alpha Diagnostics |
100 ul |
EUR 482 |
Recombinant (yeast) Human Insulin-agarose affinity support |
INSL16-AS |
Alpha Diagnostics |
0.50 ml |
EUR 286 |
Human+Bovine+Porcine Insulin-agarose affinity support |
INSL20-AS |
Alpha Diagnostics |
0.50 ml |
EUR 347 |
Sheep Anti-Digoxigenin IgG, unlabeled, affinity purified |
DGX11-A |
Alpha Diagnostics |
1 mg |
EUR 408 |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
SEE387Ra-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5124.2 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat High Affinity Choline Transporter (ChT) in Tissue homogenates, cell lysates and other biological fluids. |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
SEE387Ra-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 509.64 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat High Affinity Choline Transporter (ChT) in Tissue homogenates, cell lysates and other biological fluids. |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
SEE387Ra-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 685.2 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat High Affinity Choline Transporter (ChT) in Tissue homogenates, cell lysates and other biological fluids. |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
SEE387Ra-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2783.4 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat High Affinity Choline Transporter (ChT) in Tissue homogenates, cell lysates and other biological fluids. |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
4-SEE387Ra |
Cloud-Clone |
-
EUR 5175.00
-
EUR 2734.00
-
EUR 686.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat High Affinity Choline Transporter (ChT) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species. |
Green Fluorescent Protein Rabbit pAb, affinity pure, 25UG |
A013-25UG |
Arbor Assays |
25UG |
EUR 476 |
Human Low affinity immunoglobulin epsilon Fc receptor (FCER2) |
1-CSB-EP008534HU |
Cusabio |
-
EUR 380.00
-
EUR 214.00
-
EUR 1309.00
-
EUR 560.00
-
EUR 873.00
-
EUR 262.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Low affinity immunoglobulin epsilon Fc receptor(FCER2),partial expressed in E.coli |
Anti-SF9 Insect Cell HCP 2G affinity purified |
SF9RB01-AF |
Cygnus Technologies |
0.5 mg |
EUR 1913 |
|
Description: Anti-SF9 Insect Cell HCP 2G affinity purified by Cygnus Technologies is available in Europe via Gentaur. |
Human High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 521 |
Human High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 723 |
Mouse High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 533 |
Mouse High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 740 |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 557 |
Rat High Affinity Choline Transporter (ChT) ELISA Kit |
RD-ChT-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 775 |
Rabbit Anti-Human Haptoglobin Polyclonal Antibody(Affinity Purified) |
DPAB2047RH |
Creative Diagnostics |
1mg |
EUR 580 |
Human High Affinity Choline Transporter (ChT) ELISA Kit |
DLR-ChT-Hu-48T |
DL Develop |
48T |
EUR 517 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human High Affinity Choline Transporter (ChT) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human High Affinity Choline Transporter (ChT) ELISA Kit |
DLR-ChT-Hu-96T |
DL Develop |
96T |
EUR 673 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human High Affinity Choline Transporter (ChT) in samples from tissue homogenates, cell lysates or other biological fluids. |