autophagy pathway

IDO Pathway inhibitor
2746-50	Biovision		EUR 120.00

Autophagy Detection Kit
abx299014-50tests	Abbexa	50 tests	EUR 523.00
Shipped within 1 week.

Autophagy Detection Kit
abx299015-200tests	Abbexa	200 tests	EUR 871.00
Shipped within 1 week.

Autophagy Related 10
PR27226	Neuromics	5 ug	EUR 191.00

Autophagy Related 3
PR27227	Neuromics	5 ug	EUR 191.00

Autophagy Related 5
PR27229	Neuromics	2 ug	EUR 191.00

Autophagy Assay, Red
KF17373	Neuromics	50 Tests	EUR 278.00

Xanthohumol (Autophagy inhibitor)
SIH-370-10MG	Stressmarq	10 mg	EUR 255.00
Xanthohumol is a valosin-containing protein (VCP) inhibitor which binds to the N-domain of VCP, suppressing function and impairing autophagosome maturation (1). It also inhibits growth of a wide variety of human cancer cell lines by inhibiting prolif Show more
Description: The substance Xanthohumol is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is yellow solid which is May be dissolved in DMSO (35 mg/ml) or Ethanol (35 mg/ml).

Xanthohumol (Autophagy inhibitor)
SIH-370-50MG	Stressmarq	50 mg	EUR 855.00
Xanthohumol is a valosin-containing protein (VCP) inhibitor which binds to the N-domain of VCP, suppressing function and impairing autophagosome maturation (1). It also inhibits growth of a wide variety of human cancer cell lines by inhibiting prolif Show more
Description: The substance Xanthohumol is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is yellow solid which is May be dissolved in DMSO (35 mg/ml) or Ethanol (35 mg/ml).

Wortmannin (Autophagy inhibitor)
SIH-392-1MG	Stressmarq	1 mg	EUR 126.00
Wortmannin is a steroid metabolite from the fungi Penicillium funiculosum. It specifically and irreversibly inhibits phosphatidylinositol 3-kinase (PI3-K). This in turn has been shown to inhibit the metabolic effects of insulin, yet the insulin recep Show more
Description: The substance Wortmannin is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white solid. which is soluble in DMSO (50 mg/ml), methanol (5 mg/ml) or 100% ethanol (25 mg/ml)..

Wortmannin (Autophagy inhibitor)
SIH-392-5MG	Stressmarq	5 mg	EUR 305.00
Wortmannin is a steroid metabolite from the fungi Penicillium funiculosum. It specifically and irreversibly inhibits phosphatidylinositol 3-kinase (PI3-K). This in turn has been shown to inhibit the metabolic effects of insulin, yet the insulin recep Show more
Description: The substance Wortmannin is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white solid. which is soluble in DMSO (50 mg/ml), methanol (5 mg/ml) or 100% ethanol (25 mg/ml)..

Rottlerin (Autophagy inducer)
SIH-394-10MG	Stressmarq	10 mg	EUR 145.00
Rottlerin has been shown to inhibit protein kinase C as well as CAM kinase III. It is also a potent activator of many K+ channels which are Ca2+-activated. Studies have illustrated Rottlerin to act as a mitochondrial uncoupler which depolarizes membr Show more
Description: The substance Rottlerin is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is orange to brown solid. which is soluble to 2 mM in ethanol and to 20 mM in DMSO..

Rottlerin (Autophagy inducer)
SIH-394-50MG	Stressmarq	50 mg	EUR 377.00
Rottlerin has been shown to inhibit protein kinase C as well as CAM kinase III. It is also a potent activator of many K+ channels which are Ca2+-activated. Studies have illustrated Rottlerin to act as a mitochondrial uncoupler which depolarizes membr Show more
Description: The substance Rottlerin is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is orange to brown solid. which is soluble to 2 mM in ethanol and to 20 mM in DMSO..

Tunicamycin (Autophagy inducer)
SIH-397-25MG	Stressmarq	25 mg	EUR 541.00
As a nucleoside antibiotic, Tunicamycin blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. This causes an induction of glucose-regulated protein 78 (GRP78) mR Show more
Description: The substance Tunicamycin is a autophagy inducer. It is isolated from streptomyces lysosuperficus and has a purity of >98%. The pure substance is white solid. which is soluble in DMSO (>10 mg/ml) or ethanol (5 mg/ml; warm)..

Tunicamycin (Autophagy inducer)
SIH-397-5MG	Stressmarq	5 mg	EUR 190.00
As a nucleoside antibiotic, Tunicamycin blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. This causes an induction of glucose-regulated protein 78 (GRP78) mR Show more
Description: The substance Tunicamycin is a autophagy inducer. It is isolated from streptomyces lysosuperficus and has a purity of >98%. The pure substance is white solid. which is soluble in DMSO (>10 mg/ml) or ethanol (5 mg/ml; warm)..

Dihydroceramide (Autophagy inducer)
SIH-398-25MG	Stressmarq	25 mg	EUR 332.00
Both in yeast and mammalian systems, dihydroceramide is the reaction intermediate found immediately prior to the final reaction product in the de novo synthesis of ceramide lipids. Recent studies have revealed that an accumulation of dihydroceramide Show more
Description: The substance Dihydroceramide is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is white solid. which is soluble in ethanol (5 mg/ml) or DMSO (5 mg/ml: dissolve in hot DMSO, then cool to RT)..

Dihydroceramide (Autophagy inducer)
SIH-398-5MG	Stressmarq	5 mg	EUR 131.00
Both in yeast and mammalian systems, dihydroceramide is the reaction intermediate found immediately prior to the final reaction product in the de novo synthesis of ceramide lipids. Recent studies have revealed that an accumulation of dihydroceramide Show more
Description: The substance Dihydroceramide is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is white solid. which is soluble in ethanol (5 mg/ml) or DMSO (5 mg/ml: dissolve in hot DMSO, then cool to RT)..

Thapsigargin (Autophagy inhibitor)
SIH-399-1MG	Stressmarq	1 mg	EUR 142.00
Thapsigargin is a cell-permeable inhibitor of the sarco-endoplasmatic reticulum Ca2+-ATPase (SERCA). This inhibition causes the release of intracellular Ca2+ stores. Thapsigargin also inhibits autophagy. This is due to the induction of and an ER stre Show more
Description: The substance Thapsigargin is a autophagy inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is colorless wax or white solid. which is soluble in DMSO (20 mg/ml), 100% ethanol (20 mg/ml) or acetone..

Thapsigargin (Autophagy inhibitor)
SIH-399-5MG	Stressmarq	5 mg	EUR 377.00
Thapsigargin is a cell-permeable inhibitor of the sarco-endoplasmatic reticulum Ca2+-ATPase (SERCA). This inhibition causes the release of intracellular Ca2+ stores. Thapsigargin also inhibits autophagy. This is due to the induction of and an ER stre Show more
Description: The substance Thapsigargin is a autophagy inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is colorless wax or white solid. which is soluble in DMSO (20 mg/ml), 100% ethanol (20 mg/ml) or acetone..

Hydroxychloroquine (Autophagy inhibitor)
SIH-400-10MG	Stressmarq	10 mg	EUR 149.00
Hydroxychloroquine was first established as an anti-malarial agent, but is now being used in a variety of applications, including the inhibition of autopagy. Hydroxychloroquine is a lysosomotropic agent and therefore inhibits autophagy by obstructing Show more
Description: The substance Hydroxychloroquine is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white powder. which is soluble in greater than 20 mg/ml H2O..

Hydroxychloroquine (Autophagy inhibitor)
SIH-400-50MG	Stressmarq	50 mg	EUR 395.00
Hydroxychloroquine was first established as an anti-malarial agent, but is now being used in a variety of applications, including the inhibition of autopagy. Hydroxychloroquine is a lysosomotropic agent and therefore inhibits autophagy by obstructing Show more
Description: The substance Hydroxychloroquine is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white powder. which is soluble in greater than 20 mg/ml H2O..

Rolipram (Autophagy inhibitor)
SIH-401-10MG	Stressmarq	10 mg	EUR 149.00
Rolipram has been observed to selectively inhibit cAMP-phosphodiesterase (PDE4) by recruiting PDE4 into cytosolic aggregates that are not membrane-encapsulated. A down-stream effect of this observation is the inhibition of autophagy. Under normal con Show more
Description: The substance Rolipram is a autophagy inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white to off-white solid. which is soluble to 75 mM in DMSO and to 75 mM in ethanol..

Rolipram (Autophagy inhibitor)
SIH-401-50MG	Stressmarq	50 mg	EUR 388.00
Rolipram has been observed to selectively inhibit cAMP-phosphodiesterase (PDE4) by recruiting PDE4 into cytosolic aggregates that are not membrane-encapsulated. A down-stream effect of this observation is the inhibition of autophagy. Under normal con Show more
Description: The substance Rolipram is a autophagy inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white to off-white solid. which is soluble to 75 mM in DMSO and to 75 mM in ethanol..

AICAR (Autophagy inducer)
SIH-402-10MG	Stressmarq	10 mg	EUR 126.00
AICAR is an adenosine analog that when phosphorylated forms 5-aminoimidazole-4-carboxamide-1-D-ribofuranosyl-5'-monophosphate (ZMP) which proceeds to activate adenosine monophosphate-activated protein kinase (AMPK). This process in turn stimulates gl Show more
Description: The substance AICAR is a autophagy inducer. It is synthetically produced and has a purity of >99%. The pure substance is off-white solid. which is soluble to 75 mM in water and to 75 mM in DMSO..

AICAR (Autophagy inducer)
SIH-402-50MG	Stressmarq	50 mg	EUR 175.00
AICAR is an adenosine analog that when phosphorylated forms 5-aminoimidazole-4-carboxamide-1-D-ribofuranosyl-5'-monophosphate (ZMP) which proceeds to activate adenosine monophosphate-activated protein kinase (AMPK). This process in turn stimulates gl Show more
Description: The substance AICAR is a autophagy inducer. It is synthetically produced and has a purity of >99%. The pure substance is off-white solid. which is soluble to 75 mM in water and to 75 mM in DMSO..

Niclosamide (Autophagy inducer)
SIH-406-1G	Stressmarq	1 g	EUR 108.00
Niclosamide is part of the anthelmintics drug class, which are used to treat tapeworm infections in humans. Niclosamide has been shown to selectively inhibit the Stat-3 signalling pathway, specifically by inhibiting its activation, nuclear translocat Show more
Description: The substance Niclosamide is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is pale yellow solid which is soluble to 25 mM in ethanol and to 10 mM in DMSO.

Hh Signaling Pathway Antagonist
1659-1	Biovision		EUR 180.00

Human Calcium Regulation Pathway
HCAR-I	Real Time Primers	1 set	EUR 548.00

Human Notch Signaling Pathway
HNOT-I	Real Time Primers	1 set	EUR 548.00

Autophagy Related 10 Protein
20-abx260956	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Beclin 1, Autophagy Related
PR27257	Neuromics	2 ug	EUR 191.00

Human Autophagy Primer Library
HATPL-I	Real Time Primers	1 set	EUR 450.00

3-Methyladenine autophagy inhibitor
GL3599-100MG	Glentham Life Sciences	100 mg	EUR 189.00

3-Methyladenine autophagy inhibitor
GL3599-250MG	Glentham Life Sciences	250 mg	EUR 332.00

3-Methyladenine autophagy inhibitor
GL3599-25MG	Glentham Life Sciences	25 mg	EUR 108.00

Mouse Autophagy Primer Library
MATPL-I	Real Time Primers	1 set	EUR 450.00

DiscoveryProbe? Autophagy Compound Library
L1031-.1	ApexBio	100 uL/well(10 mM solution)	EUR 11174.00

DiscoveryProbe? Autophagy Compound Library
L1031-.25	ApexBio	250 uL/well(10 mM solution)	EUR 20118.00

DiscoveryProbe? Autophagy Compound Library
L1031-5	ApexBio	5 mg/well	EUR 26150.00

Tamoxifen Citrate (Autophagy inducer)
SIH-389-100MG	Stressmarq	100 mg	EUR 126.00
Tamoxifen citrate is an endocrine therapy drug used to treat breast cancer. It acts to interrupt estrogen signaling by blocking the estrogen receptor (ER). In vivo, tamoxifen and tamoxafin metabolites bind to estrogen receptors, causing the transcrip Show more
Description: The substance Tamoxifen Citrate is a autophagy inducer. It is synthetically produced and has a purity of ?99%. The pure substance is white to off-white powder which is soluble in methanol (50 mg/ml) or ethanol; very slightly soluble in water or acetone..

Tamoxifen Citrate (Autophagy inducer)
SIH-389-500MG	Stressmarq	500 mg	EUR 205.00
Tamoxifen citrate is an endocrine therapy drug used to treat breast cancer. It acts to interrupt estrogen signaling by blocking the estrogen receptor (ER). In vivo, tamoxifen and tamoxafin metabolites bind to estrogen receptors, causing the transcrip Show more
Description: The substance Tamoxifen Citrate is a autophagy inducer. It is synthetically produced and has a purity of ?99%. The pure substance is white to off-white powder which is soluble in methanol (50 mg/ml) or ethanol; very slightly soluble in water or acetone..

Doxorubicin Hydrochloride (Autophagy inducer)
SIH-390-10MG	Stressmarq	10 mg	EUR 193.00
Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefo Show more
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM)..

Doxorubicin Hydrochloride (Autophagy inducer)
SIH-390-50MG	Stressmarq	50 mg	EUR 529.00
Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefo Show more
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM)..

Bafilomycin A1 (Autophagy inhibitor)
SIH-391-100UG	Stressmarq	100 µg	EUR 121.00
Bafilomycin A1 is a macrolide antibiotic derived from Streptomyces griseus. It selectively inhibits vacuolar-type H+-ATPases, allowing it to be used to differentiate between different types of ATPases. Bafilomycin also acts to inhibit autophagy by ei Show more
Description: The substance Bafilomycin A1 is a autophagy inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is white powder to colorless film. which is soluble in 100% ethanol, methanol or DMSO..

Bafilomycin A1 (Autophagy inhibitor)
SIH-391-500UG	Stressmarq	500 µg	EUR 177.00
Bafilomycin A1 is a macrolide antibiotic derived from Streptomyces griseus. It selectively inhibits vacuolar-type H+-ATPases, allowing it to be used to differentiate between different types of ATPases. Bafilomycin also acts to inhibit autophagy by ei Show more
Description: The substance Bafilomycin A1 is a autophagy inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is white powder to colorless film. which is soluble in 100% ethanol, methanol or DMSO..

Amiodarone Hydrochloride (Autophagy inducer)
SIH-393-1G	Stressmarq	1 g	EUR 142.00
Amiodarone is a non-selective ion channel blocker. It has been found, when used in Saccharomyces cerevisiae, to induce an influx of Ca2+ followed by mitochondrial fragmentation and subsequent cell death. Amiodarone has also been shown to induce autop Show more
Description: The substance Amiodarone Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >99. The pure substance is white solid which is soluble to 50 mM in DMSO.

Metformin Hydrochloride (Autophagy inducer)
SIH-395-5G	Stressmarq	5 g	EUR 108.00
Metformin Hydrochloride is an antidiabetic agent which reduces blood-glucose levels as well as improves insulin sensitivity. Metformin has also been shown to inhibit hepatic gluconeogenesis via activation of LKB1-AMPK (AMP-activated protein kinase) p Show more
Description: The substance Metformin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of ?97%. The pure substance is white crystalline powder. which is soluble to 100 mM in water and to 50 mM in DMSO..

STF-62247 (Autophagy inducer)
SIH-396-10MG	Stressmarq	10 mg	EUR 153.00
STF-62247 is a selective cell-permeable inducer of autophagy. This is demonstrated by an induction of large vacuole formation in cells. This observation is especially pronounced in von Hippel-Lindau deficient renal carcinoma cells. Induction of autop Show more
Description: The substance STF-62247 is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is solid which is soluble in DMSO (26 mg/ml)..

STF-62247 (Autophagy inducer)
SIH-396-50MG	Stressmarq	50 mg	EUR 417.00
STF-62247 is a selective cell-permeable inducer of autophagy. This is demonstrated by an induction of large vacuole formation in cells. This observation is especially pronounced in von Hippel-Lindau deficient renal carcinoma cells. Induction of autop Show more
Description: The substance STF-62247 is a autophagy inducer. It is synthetically produced and has a purity of ?98%. The pure substance is solid which is soluble in DMSO (26 mg/ml)..

Spautin-1 (Autophagy inhibitor)
SIH-404-25MG	Stressmarq	25 mg	EUR 440.00
Spautin-1 inhibits the deubiquitination activity of USP10 and USP13, two ubiquitin-specific peptidases. This results in the degradation of class III PI3 kinase complexes. Because this group of kinases regulates autophagy, Spautin-1 in turn inhibits a Show more
Description: The substance Spautin-1 is a autophagy inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to beige powder. which is soluble in DMSO (15 mg/ml)..