Lékařská biotechnologická výzkumná laboratoř

Pozadí rabies viru a cílových antigenů

Virus vztekliny (Lyssavirus, rodina Rhabdoviridae) je obalený RNA virus se záporným řetězcem, který kóduje pět hlavních proteinů: N (nukleoprotein), P (fosfoprotein), M (matrix), G (glykoprotein) a L (polymeráza).
Canine Rabies Antigen …

Základní informace o Haptoglobinu (HP/Hpt)

Haptoglobin (gen HP) je plazmatický glykoprotein, který váže volný hemoglobin v cirkulaci a tvoří komplexy Hpt-Hb, jež jsou následně odstraňovány. Informace o genu, izoformách proteinu a polymorfismech lze nalézt zde:

• NCBI Gene – HP

Co to je

Rbt Xhmstr IgG F(ab’)2 Uncnj je králičí polyklonální fragment F(ab’)2 namířený proti křeččí IgG (γ-řetězec). Fc oblast je enzymaticky odstraněna, čímž se minimalizují Fc-zprostředkované interakce s Fc receptory a snižuje se nespecifické pozadí v aplikacích jako …

Precise nucleic acid quantification underpins many genomic workflows, from next-generation sequencing to RNA profiling. Among available tools, the Qubit Assay Kit series stands out for its sensitivity, specificity, and ease of use. Researchers often face the challenge of selecting the …

Introduction

Polymerase Chain Reaction (PCR) is widely used in molecular biology to amplify DNA sequences for research and diagnostic applications. Ensuring PCR assay accuracy requires robust qualitative quality control (QC) to detect non-specific amplifications and validate results. Digital tools for …

The advancement of lipid nanoparticle (LNP) kits has significantly improved the field of fast immunocyte delivery by providing a reliable platform for in vitro delivery of nucleic acids into immune cells. These kits enable efficient and gentle nucleic acid delivery…

Introduction to UltraNuclease and Its Importance

UltraNuclease enzymes, also known as non-restrictive endonucleases or broad-spectrum nucleases, are specialized enzymes capable of cleaving both DNA and RNA with high efficiency. These enzymes are widely used in molecular biology for nucleic …

Construct validation remains an essential checkpoint in molecular cloning workflows, verifying that the DNA fragment is correctly inserted into the vector before functional studies. This comprehensive guide outlines the complete pipeline—from vector preparation to clone verification—highlighting modern cloning technologies like …

The advancement of drug development and toxicology research heavily relies on precise and robust methods to evaluate cellular metabolism. Metabolism assay kits serve as vital tools for investigating how chemical entities influence cellular bioenergetics, metabolic pathways, and enzyme functions. These …

Melatonin, a small indoleamine molecule synthesized primarily by the pineal gland, plays a central role in circadian biology and photoperiodic regulation. The General Melatonin ELISA (Enzyme-Linked Immunosorbent Assay) is a specialized tool developed to measure the concentration of …