DESCRIPTION
Amino Acid Sequence
General description
Application
Amyloid β Protein Fragment 1-40 has been used:
- in the temperature based conformational studies using Fourier transform infrared/differential scanning calorimetry (FT-IR/DSC) studies
- as a reference standard in sandwich-type enzyme immunoassay for quantifying amyloid A4 protein in cerebrospinal fluid of patients with head trauma
- as a component of embryonic stem cell medium to inhibit amyloid deposition in fibroblasts
Biochem/physiol Actions
Reconstitution
Other Notes

amyloid
Abstract
Alzheimer’s disease (AD) pathogenesis is widely believed to be driven by the production and deposition of the β-amyloid peptide (Aβ). For many years, investigators have been puzzled by the weak to nonexistent correlation between the amount of neuritic plaque pathology in the human brain and the degree of clinical dementia. Recent advances in our understanding of the development of amyloid pathology have helped solve this mystery. Substantial evidence now indicates that the solubility of Aβ, and the quantity of Aβ in different pools, may be more closely related to disease state. The composition of these pools of Aβ reflects different populations of amyloid deposits, and has definite correlates with the clinical status of the patient. Imaging technologies, including new amyloid imaging agents based on the chemical structure of histologic dyes, are now making it possible to track amyloid pathology along with disease progression in the living patient. Interestingly, these approaches indicate that the Aβ deposited in AD is different from that found in animal models. In general, deposited Aβ is more easily cleared from the brain in animal models, and does not show the same physical and biochemical characteristics as the amyloid found in AD. This raises important issues regarding the development and testing of future therapeutic agents.
Beta Amyloid |
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MO22142 | Neuromics | 100 ul | EUR 435 |
beta Amyloid 40 protein |
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30R-3013 | Fitzgerald | 500 ug | EUR 327 |
Description: Purified recombinant beta Amyloid 40 protein |
beta Amyloid 42 protein |
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30R-3014 | Fitzgerald | 500 ug | EUR 327 |
Description: Purified recombinant beta Amyloid 42 protein |
beta-Amyloid antibody |
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22965-100ul | SAB | 100ul | EUR 390 |
beta Amyloid Antibody |
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35506-100ul | SAB | 100ul | EUR 390 |
beta Amyloid antibody |
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20R-AR011 | Fitzgerald | 250 ul | EUR 381 |
Description: Rabbit polyclonal beta Amyloid antibody |
beta Amyloid antibody |
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10R-7917 | Fitzgerald | 100 ug | EUR 322 |
Description: Mouse monoclonal beta Amyloid antibody |
beta Amyloid antibody |
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10R-A124a | Fitzgerald | 50 ug | EUR 1011 |
Description: Mouse monoclonal beta Amyloid antibody |
beta Amyloid antibody |
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70R-10624 | Fitzgerald | 1 ml | EUR 693 |
Description: Affinity purified Chicken polyclonal beta Amyloid antibody |
beta Amyloid antibody |
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70R-12571 | Fitzgerald | 100 ul | EUR 457 |
Description: Affinity purified Rabbit polyclonal beta Amyloid antibody |
Beta Amyloid antibody |
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70R-51450 | Fitzgerald | 100 ul | EUR 287 |
Description: Purified Polyclonal Beta Amyloid antibody |
beta Amyloid antibody |
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70R-AR020 | Fitzgerald | 100 ug | EUR 300 |
Description: Affinity purified Rabbit polyclonal beta Amyloid antibody |
beta Amyloid antibody |
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70R-BR019 | Fitzgerald | 100 ug | EUR 300 |
Description: Affinity purified Rabbit polyclonal beta Amyloid antibody |
Amyloid Beta (A4) Precursor Protein |
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PR27172 | Neuromics | 10 ug | EUR 318 |
Amyloid beta-Protein (1-43) |
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5-00662 | CHI Scientific | 4 x 1mg | Ask for price |
Amyloid beta-Protein (20-29) |
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5-00663 | CHI Scientific | 4 x 5mg | Ask for price |
Amyloid beta-Protein (29-40) |
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5-00665 | CHI Scientific | 4 x 1mg | Ask for price |
Amyloid beta-Protein (33-42) |
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5-00666 | CHI Scientific | 4 x 5mg | Ask for price |
Amyloid beta-Protein (42-1) |
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5-00667 | CHI Scientific | 4 x 1mg | Ask for price |
Amyloid beta-Protein (6-20) |
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5-00668 | CHI Scientific | 4 x 1mg | Ask for price |
Amyloid beta 1-42 Protein |
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abx060277-100ug | Abbexa | 100 ug | EUR 759 |